Structure and function of the hybrid cluster protein

A hybrid cluster (HC) is a 4Fe with both sulfur and oxygen bridges. Hybrid proteins (Hcps) contain two clusters, one electron transferring iron-sulfur cluster. The structural gene, hcp, diffusely found in bacteria, archaea, monocellular eukarya, the HC binding motif involving amino acids H, E, C, (K) appears to be fully conserved. active site of enzyme Hcp. Of several reported Hcp enzymatic activities conversion nitric oxide into nitrous oxide, NO reductase, has been established as physiologically relevant. Other activities, notably signal transduction by transfer other proteins, are controversial. undergoes complex change associated single-electron iron based redox chemistry well electron-pair persulfidocysteine atom. mechanistic scheme proposed for encompassing its structural, magnetic, properties.